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Multi-laser Combiner
Definition for Multi-line Laser/ Multi-wavelength Laser
It refers to one light source formed by combining multiple light sources through technical means.These multiple light sources can be combined for single-channel output or output through separate channels. Generally, each channel can be independently controlled for turning on/off and power adjustment, operating both independently and collaboratively. Compared with traditional single-wavelength light sources, multi-wavelength light sources are widely used in fields such as biomedicine, scientific research, materials science, and industrial processing due to their high flexibility and adaptability.
Classification
(1) Multi-wavelength LED light source
The multi-wavelength LED light source (SLE Light Engine) is an illumination system composed of multiple LEDs. It is mainly based on the solid-state lighting technology of light-emitting diodes (LEDs) and is widely used in microscope imaging and other life science fields. It is used to excite GFP/FITC, DAPI, YFP, mCherry, Cy3, Cy5 and spectrally similar fluorophores. CNI's SLE solid-state light engines include typical products with four-wavelength and six-wavelength combinations, and custom services are also available.
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Four-wavelength SLE Light Engine (365/ 470 /555/ 630) | Six-wavelengthSLE Light Engine |
(2) Multi-wavelength laser source
CNI's multi-wavelength laser can achieve beam combining of 2-20 wavelengths, with a wavelength range covering ultraviolet to near-infrared. Compared with multi-wavelength LED combined light sources, it features high power, diverse wavelength options, and versatile beam spot modes, making it widely used in fields such as DNA sequencing, PCR detection, confocal microscopy, flow cytometry, biomedicine, and full-color holography.
Typical products of multi-wavelength lasers
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Multi-wavelength Free Space | Multi-wavelength SM Fiber |
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Multi-wavelength MM Fber | OEM Laser Combiner |
Typical applications of multi-wavelength beam-combining sources
(1) Confocal fluorescence microscopy
Confocal fluorescence microscopy builds upon traditional fluorescence microscopy by incorporating a laser scanning system and leveraging computer-based image processing. This advanced technique enables not only the observation of cells and tissue sections in solid samples but also real-time, dynamic imaging and detection of structures, molecules, and ions within living cells. Typical excitation wavelengths include 405 nm, 488 nm, 561 nm, and 640 nm. A key technological breakthrough lies in the long-term, stable, and reliable output of multi-wavelength single-mode polarization-maintaining optical fibers. CNI offers highly dependable, integrated confocal microscopy light source solutions tailored to meet precision imaging needs.
Confocal microscopy light sources (405 nm, 488 nm, 561 nm, 640 nm)
(2) Flow Cytometry
Flow cytometry integrates laser technology, electrophysics, fluid dynamics, optoelectronic measurement techniques, computer technology, and monoclonal antibody technology into a single, powerful tool—a novel analytical and sorting technique capable of rapidly analyzing cellular (or subcellular) structures. It is widely used in clinical and basic medical research fields such as immunology, hematology, oncology, cell biology, cytogenetics, and biochemistry. Typical laser wavelengths for flow cytometers include 405 nm, 488 nm, 532 nm, 561 nm, 640 nm, and 785 nm. These instruments place extremely stringent demands on the light source, particularly regarding beam ellipticity, noise levels, and stability. In addition to these standard wavelength combinations, CNI can customize multi-wavelength flow cytometer light sources tailored to specific research needs.
Principle of Flow Cytometry
Changchun New Industries Optoelectronics Technology Co., Ltd.
Address: No. 888 Jinhu Road, High-Tech Zone, Changchun, 130103, P.R.China
International Tel:+86-431-85603799
Email: sales@cnilaser.com
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